![]() ![]() 3, 4 High taurine levels appear to be cardioprotective in patients with elevated cholesterol levels. On the cellular level, it is involved in the regulation of the calcium and magnesium balance and in the stabilization of the heart muscle cells. Taurine has positive inotropic, antihypertensive and antiarrhythmic effects. ![]() Taurine for support of cardiovascular diseases Taurine protects the membranes of the tubule epithelium and glomeruli from lipid oxidation in vitro and in vivo. Oxidative processes can damage the glomeruli membranes and thus promote the development of kidney diseases. In chronic renal insufficiency, significantly reduced levels of antioxidant taurine in tissue and plasma can be observed. The kidneys play an important role in maintaining the concentration of physiological taurine. Renal insufficiency disturbs taurine balance Studies suggest that taurine reduces the risk of gallstones. 4 The bile acids synthesized from cholesterol in the liver are secreted into the small intestine as taurine conjugates. Together with glycine it is essential for the metabolism of bile acids and fat absorption. Thanks to pronounced antioxidative effects, taurine protects cell membranes and tissue such as the retina of the eye from oxidative damage and is also involved in the detoxification of potentially toxic endogenous and exogenous compounds such as xenobiotics. ![]() The endogenous synthesis rate is then not sufficient to cover the increased demand or to compensate for the depletion rates. Taurine belongs to this group because metabolic stress leads to tissue depletion of this amino acid. Such amino acids are called conditionally essential. 3 Individual non-essential amino acids can become essential under certain conditions. The central nervous system, the eye lens and the blood platelets are particularly rich in taurine. 2 After glutamine, taurine is the most concentrated amino acid in the free amino acid pool. 1 As a component of breast milk, this amino acid derivative is involved in brain development and the visual process of adolescents. Taurine is nevertheless essential for infants and premature babies. In contrast to other amino acids, taurine is not used to produce protein in the body and is therefore not proteinogenic. Taurine is a sulfur-containing, antioxidant amino acid derivative, which is formed in the liver from L-cysteine or L-methionine with vitamin-B6 involvement. Highest dosage without negative effects as published in studies (unofficial value)ĭetailed information Conditionally essential amino acid taurine Reference value according to the food labelling regulation Radiotherapy, cytotoxics, infants, for eye diseases, cardiovascular diseases, vegan diet, lack of cofactors (vitamin B6, cysteine, methionine) Stimulation of the inflow and membrane binding of calciumĪntiarrhythmic and a positive inotropic effect on the heart through stabilisation of the membrane potentialĪnti-inflammatory effect through reduction of TNF-α productionĪs an antioxidant it protects e.g. Important role in fat metabolism through formation of bile acid conjugates Fish and meat in particular provide high amounts of taurine, although the content is much higher when muscles are used intensively (e.g. While mixed diets provide an additional 50 - 400 mg of taurine via the diet, vegetarians hardly consume any taurine. Taurine is a sulfur-containing amino acid derivative that can be synthesized by the body. Sources and physiological effects Dietary sources ![]()
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